DEFB106A (NM_152251) Human Mass Spec Standard

Specifications

Product Data
Description	DEFB106A MS Standard C13 and N15-labeled recombinant protein (NP_689464)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC219477
Predicted MW	7.4 kDa
Protein Sequence	Sequence Link (showhide) >RC219477 protein sequence Red=Cloning site Green=Tags(s) MRTFLFLFAVLFFLTPAKNAFFDEKCNKLKGTCKNNCGKNEELIALCQKSLKCCRTIQPCGSIID TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_689464
RefSeq Size	325
RefSeq ORF	195
Synonyms	BD-6; DEFB-6; DEFB106
Locus ID	245909
Cytogenetics	8p23.1
Summary	Defensins form a family of antimicrobial and cytotoxic peptides made by neutrophils. Defensins are short, processed peptide molecules that are classified by structure into three groups: alpha-defensins, beta-defensins and theta-defensins. All beta-defensin genes are densely clustered in four to five syntenic chromosomal regions. Chromosome 8p23 contains at least two copies of the duplicated beta-defensin cluster. This duplication results in two identical copies of defensin, beta 106, DEFB106A and DEFB106B, in head-to-head orientation. This gene, DEFB106A, represents the more centromeric copy. [provided by RefSeq, Oct 2014]
Protein Families	Secreted Protein

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