RbAp46 (RBBP7) (NM_002893) Human Mass Spec Standard

CAT#: PH317969

RBBP7 MS Standard C13 and N15-labeled recombinant protein (NP_002884)



  View other "RbAp46" proteins (5)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description RBBP7 MS Standard C13 and N15-labeled recombinant protein (NP_002884)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC217969
Predicted MW 47.8 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_002884
RefSeq Size 2021
RefSeq ORF 1275
Synonyms RbAp46
Locus ID 5931
Cytogenetics Xp22.2
Summary This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Protein Families Druggable Genome
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