FAM36A (COX20) (NM_198076) Human Mass Spec Standard

Specifications

Product Data
Description	FAM36A MS Standard C13 and N15-labeled recombinant protein (NP_932342)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC217381
Predicted MW	13.3 kDa
Protein Sequence	Sequence Link (showhide) >RC217381 protein sequence Red=Cloning site Green=Tags(s) MAAPPEPGEPEERKSLKLLGFLDVENTPCARHSILYGSLGSVVAGFGHFLFTSRIRRSCDVGVGGFILVT LGCWFHCRYNYAKQRIQERIAREEIKKKILYEGTHLDPERKHNGSSSN TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_932342
RefSeq Size	2632
RefSeq ORF	354
Synonyms	FAM36A; MC4DN11
Locus ID	116228
Cytogenetics	1q44
Summary	This gene encodes a protein that plays a role in the assembly of cytochrome C oxidase, an important component of the respiratory pathway. It contains two transmembrane helices and localizes to the mitochondrial membrane. Mutations in this gene can cause mitochondrial complex IV deficiency, which results in ataxia and muscle hypotonia. There are multiple pseudogenes for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]

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