STAT1 (NM_007315) Human Mass Spec Standard

CAT#: PH313858

STAT1 MS Standard C13 and N15-labeled recombinant protein (NP_009330)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description STAT1 MS Standard C13 and N15-labeled recombinant protein (NP_009330)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC213858
Predicted MW 87.2 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_009330
RefSeq Size 4157
RefSeq ORF 2250
Synonyms CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91
Locus ID 6772
Cytogenetics 2q32.2
Summary The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. The protein encoded by this gene can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. The protein plays an important role in immune responses to viral, fungal and mycobacterial pathogens. Mutations in this gene are associated with Immunodeficiency 31B, 31A, and 31C. [provided by RefSeq, Jun 2020]
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Chemokine signaling pathway, Jak-STAT signaling pathway, Pancreatic cancer, Pathways in cancer, Toll-like receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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