Tau (MAPT) (NM_005910) Human Mass Spec Standard

CAT#: PH313312

MAPT MS Standard C13 and N15-labeled recombinant protein (NP_005901)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

Cited in 1 publication.

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Specifications

Product Data
Description MAPT MS Standard C13 and N15-labeled recombinant protein (NP_005901)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC213312
Predicted MW 45.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_005901
RefSeq Size 5731
RefSeq ORF 1323
Synonyms DDPAC; FTDP-17; MAPTL; MSTD; MTBT1; MTBT2; PPND; PPP1R103; TAU; tau-40
Locus ID 4137
Cytogenetics 17q21.31
Summary This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
Protein Pathways Alzheimer's disease, MAPK signaling pathway
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