SHISA3 (NM_001080505) Human Mass Spec Standard

Specifications

Product Data
Description	SHISA3 MS Standard C13 and N15-labeled recombinant protein (NP_001073974)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC212334
Predicted MW	25.7 kDa
Protein Sequence	Sequence Link (showhide) >RC212334 protein sequence Red=Cloning site Green=Tags(s) MRALLALCLLLGCLRWGPAGAQQSGEYCHGWVDVQGNYHEGFQCPEDFDTLDATICCGSCALRYCCAAAD ARLEQGGCTNDRRELEHPGITAQPVYVPFLIVGSIFIAFIILGSVVAIYCCTCLRPKEPSQQPIRFSLRS YQTETLPMILTSTSPRAPSRQSSTATSSSSTGGSIRRFSFARAEPGCLVPSPPPPYTTSHSIHLAQPSGF LVSPQYFAYPLQQEPPLPGKSCPDFSSS TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001073974
RefSeq Size	1971
RefSeq ORF	714
Synonyms	hShisa3
Locus ID	152573
Cytogenetics	4p13
Summary	This gene encodes a single-transmembrane protein which is one of nine members of a family of transmembrane adaptors that modulate both WNT and FGF signaling by blocking the maturation and transport of their receptors to the cell surface. Members of this family contain an N-terminal cysteine-rich domain with a distinct cysteine pattern, a single transmembrane domain, and a C-terminal proline-rich, low complexity region. The encoded protein acts as a tumor suppressor by accelerating beta-catenin degradation. [provided by RefSeq, Jul 2017]
Protein Families	Transmembrane

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