FKBP51 (FKBP5) (NM_004117) Human Mass Spec Standard

CAT#: PH310608

FKBP5 MS Standard C13 and N15-labeled recombinant protein (NP_004108)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description FKBP5 MS Standard C13 and N15-labeled recombinant protein (NP_004108)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC210608
Predicted MW 51 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_004108
RefSeq Size 3781
RefSeq ORF 1371
Synonyms AIG6; FKBP51; FKBP54; P54; PPIase; Ptg-10
Locus ID 2289
Cytogenetics 6p21.31
Summary The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]
Protein Families Druggable Genome
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