Nucleophosmin (NPM1) (NM_001037738) Human Mass Spec Standard
CAT#: PH310458
NPM1 MS Standard C13 and N15-labeled recombinant protein (NP_001032827)
View other "Nucleophosmin" proteins (11)
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CNY 19,520.00
Cited in 1 publication. |
Specifications
Product Data | |
Description | NPM1 MS Standard C13 and N15-labeled recombinant protein (NP_001032827) |
Species | Human |
Expression Host | HEK293 |
Expression cDNA Clone or AA Sequence | RC210458 |
Predicted MW | 28.4 kDa |
Protein Sequence |
>RC210458 protein sequence
Red=Cloning site Green=Tags(s) MEDSMDMDMSPLRPQNYLFGCELKADKDYHFKVDNDENEHQLSLRTVSLGAGAKDELHIVEAEAMNYEGS PIKVTLATLKMSVQPTVSLGGFEITPPVVLRLKCGSGPVHISGQHLVAVEEDAESEDEEEEDVKLLSISG KRSAPGGGSKVPQKKVKLAADEDDDDDDEEDDDEDDDDDDFDDEEAEEKAPVKKSIRDTPAKNAQKSNQN GKDSKPSSTPRSKGQESFKKQEKTPKTPKGPSSVEDIKAKMQASIEKAH TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Labeling Method | Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3 |
Reference Data | |
RefSeq | NP_001032827 |
RefSeq Size | 1347 |
RefSeq ORF | 777 |
Synonyms | B23; NPM |
Locus ID | 4869 |
Cytogenetics | 5q35.1 |
Summary | The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified. [provided by RefSeq, Aug 2017] |
Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
Citations (1)
The use of this Proteins has been cited in the following citations: |
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GIT1/βPIX signaling proteins and PAK1 kinase regulate microtubule nucleation.
,null,
Biochimica et biophysica acta
,PubMed ID 27012601
[NPM1]
|
Documents
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC404681 | NPM1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC419282 | NPM1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC421985 | NPM1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY404681 | Transient overexpression lysate of nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 2 |
CNY 3,080.00 |
|
LY419282 | Transient overexpression lysate of nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 1 |
CNY 3,080.00 |
|
LY421985 | Transient overexpression lysate of nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 3 |
CNY 3,080.00 |
|
PH303344 | NPM1 MS Standard C13 and N15-labeled recombinant protein (NP_002511) |
CNY 19,520.00 |
|
PH303841 | NPM1 MS Standard C13 and N15-labeled recombinant protein (NP_954654) |
CNY 19,520.00 |
|
TP303344 | Recombinant protein of human nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 1, 20 µg |
CNY 2,900.00 |
|
TP303841 | Recombinant protein of human nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 2, 20 µg |
CNY 2,900.00 |
|
TP310458 | Recombinant protein of human nucleophosmin (nucleolar phosphoprotein B23, numatrin) (NPM1), transcript variant 3, 20 µg |
CNY 2,900.00 |
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