ENSA (NM_207168) Human Mass Spec Standard

CAT#: PH309655

ENSA MS Standard C13 and N15-labeled recombinant protein (NP_997051)



  View other "ENSA" proteins (9)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description ENSA MS Standard C13 and N15-labeled recombinant protein (NP_997051)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209655
Predicted MW 12 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_997051
RefSeq Size 771
RefSeq ORF 315
Synonyms ARPP-19e
Locus ID 2029
Cytogenetics 1q21.3
Summary The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
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