Peroxiredoxin 2 (PRDX2) (NM_181738) Human Mass Spec Standard

CAT#: PH309548

PRDX2 MS Standard C13 and N15-labeled recombinant protein (NP_859428)



  View other "Peroxiredoxin 2" proteins (9)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Specifications

Product Data
Description PRDX2 MS Standard C13 and N15-labeled recombinant protein (NP_859428)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC209548
Predicted MW 15.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_859428
RefSeq Size 710
RefSeq ORF 426
Synonyms NKEFB; PRP; PRX2; PRXII; PTX1; TDPX1; TPX1; TSA
Locus ID 7001
Cytogenetics 19p13.13
Summary This gene encodes a member of the peroxiredoxin family of antioxidant enzymes, which reduce hydrogen peroxide and alkyl hydroperoxides. The encoded protein plays an antioxidant protective role in cells, and it may contribute to the antiviral activity of CD8(+) T-cells. The crystal structure of this protein has been resolved to 2.7 angstroms. This protein prevents hemolytic anemia from oxidative stress by stabilizing hemoglobin, thus making this gene a therapeutic target for patients with hemolytic anemia. This protein may have a proliferative effect and play a role in cancer development or progression. Related pseudogenes have been identified on chromosomes 5, 6, 10 and 13. [provided by RefSeq, Mar 2013]
Protein Families Druggable Genome
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