NAA40 (NM_024771) Human Mass Spec Standard

Specifications

Product Data
Description	NAA40 MS Standard C13 and N15-labeled recombinant protein (NP_079047)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC208314
Predicted MW	27.2 kDa
Protein Sequence	Sequence Link (showhide) >RC208314 protein sequence Red=Cloning site Green=Tags(s) MGRKSSKAKEKKQKRLEERAAMDAVCAKVDAANRLGDPLEAFPVFKKYDRNGLNVSIECKRVSGLEPATV DWAFDLTKTNMQTMYEQSEWGWKDREKREEMTDDRAWYLIAWENSSVPVAFSHFRFDVECGDEVLYCYEV QLESKVRRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCS YEILSRRTKFGDSHHSHAGGHCGGCCH TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_079047
RefSeq Size	3681
RefSeq ORF	711
Synonyms	hNatD; NAT11; NatD; PATT1
Locus ID	79829
Cytogenetics	11q13.1
Summary	N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A (PubMed:21935442, PubMed:25619998). In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence' (PubMed:21935442, PubMed:25619998). Acts as a negative regulator of apoptosis (PubMed:26666750). May play a role in hepatic lipid metabolism (By similarity).[UniProtKB/Swiss-Prot Function]

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