Profilin 2 (PFN2) (NM_053024) Human Mass Spec Standard

Specifications

Product Data
Description	PFN2 MS Standard C13 and N15-labeled recombinant protein (NP_444252)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC207366
Predicted MW	15 kDa
Protein Sequence	Sequence Link (showhide) >RC207366 protein sequence Red=Cloning site Green=Tags(s) MAGWQSYVDNLMCDGCCQEAAIVGYCDAKYVWAATAGGVFQSITPIEIDMIVGKDREGFFTNGLTLGAKK CSVIRDSLYVDGDCTMDIRTKSQGGEPTYNVAVGRAGRVLVFVMGKEGVHGGGLNKKAYSMAKYLRDSGF TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_444252
RefSeq Size	2117
RefSeq ORF	420
Synonyms	D3S1319E; PFL
Locus ID	5217
Cytogenetics	3q25.1
Summary	The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. [provided by RefSeq, Jul 2008]
Protein Families	Druggable Genome
Protein Pathways	Regulation of actin cytoskeleton

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