Ubiquilin (UBQLN1) (NM_013438) Human Mass Spec Standard

CAT#: PH306897

UBQLN1 MS Standard C13 and N15-labeled recombinant protein (NP_038466)



  View other "Ubiquilin" proteins (7)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Transient overexpression lysate of ubiquilin 1 (UBQLN1), transcript variant 2
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Specifications

Product Data
Description UBQLN1 MS Standard C13 and N15-labeled recombinant protein (NP_038466)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC206897
Predicted MW 62.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_038466
RefSeq Size 4177
RefSeq ORF 1767
Synonyms DA41; DSK2; PLIC-1; UBQN; XDRP1
Locus ID 29979
Cytogenetics 9q21.2-q21.3
Summary This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome
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