Ceramide glucosyltransferase (UGCG) (NM_003358) Human Mass Spec Standard

Specifications

Product Data
Description	UGCG MS Standard C13 and N15-labeled recombinant protein (NP_003349)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC206288
Predicted MW	44.9 kDa
Protein Sequence	Sequence Link (showhide) >RC206288 protein sequence Red=Cloning site Green=Tags(s) MALLDLALEGMAVFGFVLFLVLWLMHFMAIIYTRLHLNKKATDKQPYSKLPGVSLLKPLKGVDPNLINNL ETFFELDYPKYEVLLCVQDHDDPAIDVCKKLLGKYPNVDARLFIGGKKVGINPKINNLMPGYEVAKYDLI WICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGFAATLEQVYFGTSHPRYYISANVTGFKCVTG MSCLMRKDVLDQAGGLIAFAQYIAEDYFMAKAIADRGWRFAMSTQVAMQNSGSYSISQFQSRMIRWTKLR INMLPATIICEPISECFVASLIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYA VAWFIRESMTIYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_003349
RefSeq Size	1637
RefSeq ORF	1182
Synonyms	GCS; GLCT1
Locus ID	7357
Cytogenetics	9q31.3
Summary	This gene encodes an enzyme that catalyzes the first glycosylation step in the biosynthesis of glycosphingolipids, which are membrane components containing lipid and sugar moieties. The product of this reaction is glucosylceramide, which is the core structure of many glycosphingolipids. [provided by RefSeq, Dec 2014]
Protein Families	Transmembrane
Protein Pathways	Metabolic pathways, Sphingolipid metabolism

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