NKIRAS1 (NM_020345) Human Mass Spec Standard

CAT#: PH304248

NKIRAS1 MS Standard C13 and N15-labeled recombinant protein (NP_065078)



  View other "NKIRAS1" proteins (3)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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经常一起买 (2)
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Specifications

Product Data
Description NKIRAS1 MS Standard C13 and N15-labeled recombinant protein (NP_065078)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC204248
Predicted MW 21.6 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_065078
RefSeq Size 2013
RefSeq ORF 576
Synonyms kappaB-Ras1; KBRAS1
Locus ID 28512
Cytogenetics 3p24.2
Summary Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP- and GDP-bound forms block phosphorylation of NFKBIB.[UniProtKB/Swiss-Prot Function]
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