CCDC53 (WASHC3) (NM_016053) Human Mass Spec Standard

Specifications

Product Data
Description	CCDC53 MS Standard C13 and N15-labeled recombinant protein (NP_057137)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC203045
Predicted MW	21.1 kDa
Protein Sequence	Sequence Link (showhide) >RC203045 protein sequence Red=Cloning site Green=Tags(s) MDEDGLPLMGSGIDLTKVPAIQQKRTVAFLNQFVVHTVQFLNRFSTVCEEKLADLSLRIQQIETTLNILD AKLSSIPGLDDVTVEVSPLNVTSVTNGAHPEATSEQPQQSSTQDSGLQESEVSAENILTVAKDPRYARYL KMVQVGVPVMAIRNKMISEGLDPDLLERPDAPVPDGESEKTVEESSDSESSFSD TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_057137
RefSeq Size	1015
RefSeq ORF	582
Synonyms	CCDC53; CGI-116
Locus ID	51019
Cytogenetics	12q23.2
Summary	Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093).[UniProtKB/Swiss-Prot Function]

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