ARL 1 (ARL1) (NM_001177) Human Mass Spec Standard

Specifications

Product Data
Description	ARL1 MS Standard C13 and N15-labeled recombinant protein (NP_001168)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC202698
Predicted MW	20.4 kDa
Protein Sequence	Sequence Link (showhide) >RC202698 protein sequence Red=Cloning site Green=Tags(s) MGGFFSSIFSSLFGTREMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKNLKFQVWDLGG QTSIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAILVVFANKQDMEQAMTSSEMA NSLGLPALKDRKWQIFKTSATKGTGLDEAMEWLVETLKSRQ TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_001168
RefSeq Size	3253
RefSeq ORF	543
Synonyms	ARFL1
Locus ID	400
Cytogenetics	12q23.2
Summary	The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]

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