Calpastatin (CAST) (NM_001042444) Human Mass Spec Standard

CAT#: PH302168

CAST MS Standard C13 and N15-labeled recombinant protein (NP_001035909)



  View other "Calpastatin" proteins (13)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Specifications

Product Data
Description CAST MS Standard C13 and N15-labeled recombinant protein (NP_001035909)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC202168
Predicted MW 71.9 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001035909
RefSeq Size 4366
RefSeq ORF 2001
Synonyms BS-17; PLACK
Locus ID 831
Cytogenetics 5q15
Summary The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010]
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