DARPP32 (PPP1R1B) (NM_181505) Human Mass Spec Standard

Specifications

Product Data
Description	PPP1R1B MS Standard C13 and N15-labeled recombinant protein (NP_852606)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200916
Predicted MW	18.7 kDa
Protein Sequence	Sequence Link (showhide) >RC200916 protein sequence Red=Cloning site Green=Tags(s) MLFRLSEHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEED ELGELRELGYPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQGLEGPWERPPPLDESERDG GSEDQVEDPALSEPGEEPQRPSPSEPGT TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_852606
RefSeq Size	1530
RefSeq ORF	504
Synonyms	DARPP-32; DARPP32
Locus ID	84152
Cytogenetics	17q12
Summary	This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Protein Families	Druggable Genome

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