PPME1 (NM_016147) Human Mass Spec Standard

Specifications

Product Data
Description	PPME1 MS Standard C13 and N15-labeled recombinant protein (NP_057231)
Species	Human
Expression Host	HEK293
Expression cDNA Clone or AA Sequence	RC200009
Predicted MW	42.1 kDa
Protein Sequence	Sequence Link (showhide) RC200009
Tag	C-Myc/DDK
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration	>0.05 µg/µL as determined by microplate BCA method
Labeling Method	Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq	NP_057231
RefSeq Size	2484
RefSeq ORF	1158
Synonyms	ABDH19; PME-1
Locus ID	51400
Cytogenetics	11q13.4
Summary	This gene encodes a protein phosphatase methylesterase localized to the nucleus. The encoded protein acts on the protein phosphatase-2A catalytic subunit and supports the ERK pathway through dephosphorylation of regulatory proteins. It plays a role in malignant glioma progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Protein Families	Druggable Genome

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