CHD1L Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA	mBFP-Neo
Symbol	CHD1L
Locus ID	9557
Kit Components	KN223499G1, CHD1L gRNA vector 1 in pCas-Guide CRISPR vector KN223499G2, CHD1L gRNA vector 2 in pCas-Guide CRISPR vector KN223499BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_001256336, NM_001256337, NM_001256338, NM_004284, NM_024568, NR_046070, NM_001348451, NM_001348452, NM_001348453, NM_001348454, NM_001348455, NM_001348456, NM_001348457, NM_001348458, NM_001348459, NM_001348460, NM_001348461, NM_001348462, NM_001348463, NM_001348464, NM_001348465, NM_001348466, NR_145681, NR_145682, NR_145683, NR_145684, NR_145685, NR_145686, NR_145687, NR_145688, NR_145689, NR_145690, NR_145691, NR_145692, NR_145693, NR_145694, NR_145695
Synonyms	ALC1; CHDL
Summary	This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Overexpression of this gene has been linked to several types of cancers. [provided by RefSeq, Feb 2017]

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