C19orf80 (ANGPTL8) Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA	RFP-BSD
Symbol	C19orf80
Locus ID	55908
Kit Components	KN218000G1, C19orf80 gRNA vector 1 in pCas-Guide CRISPR vector KN218000G2, C19orf80 gRNA vector 2 in pCas-Guide CRISPR vector KN218000RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_018687
Synonyms	C19orf80; PRO1185; PVPA599; RIFL; TD26
Summary	Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels (PubMed:22569073, PubMed:22809513, PubMed:23150577). May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state (By similarity).[UniProtKB/Swiss-Prot Function]

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