JMJD1C Human Gene Knockout Kit (CRISPR)

CAT#: KN214878RB

JMJD1C - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


JMJD1C Rabbit polyclonal Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


JMJD1C (Myc-DDK-tagged)-Human jumonji domain containing 1C (JMJD1C), transcript variant 1
    • 10 ug

CNY 16,768.00

Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol JMJD1C
Locus ID 221037
Kit Components

KN214878G1, JMJD1C gRNA vector 1 in pCas-Guide CRISPR vector

KN214878G2, JMJD1C gRNA vector 2 in pCas-Guide CRISPR vector

KN214878RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001282948, NM_001318153, NM_001318154, NM_004241, NM_032776, NR_134512, NM_001322252, NM_001322254, NM_001322258
Synonyms TRIP8
Summary The protein encoded by this gene interacts with thyroid hormone receptors and contains a jumonji domain. It is a candidate histone demethylase and is thought to be a coactivator for key transcription factors. It plays a role in the DNA-damage response pathway by demethylating the mediator of DNA damage checkpoint 1 (MDC1) protein, and is required for the survival of acute myeloid leukemia. Mutations in this gene are associated with Rett syndrome and intellectual disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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