NUMB Human Gene Knockout Kit (CRISPR)

CAT#: KN209744RB

NUMB - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


NUMB mouse monoclonal antibody, clone OTI4F3 (formerly 4F3)
    • 100 ul

CNY 1,999.00
CNY 2,700.00


NUMB (Myc-DDK-tagged)-Human numb homolog (Drosophila) (NUMB), transcript variant 1
    • 10 ug

CNY 7,272.00

Specifications

Product Data
Format 2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA RFP-BSD
Symbol NUMB
Locus ID 8650
Kit Components

KN209744G1, NUMB gRNA vector 1 in pCas-Guide CRISPR vector

KN209744G2, NUMB gRNA vector 2 in pCas-Guide CRISPR vector

KN209744RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001005743, NM_001005744, NM_001005745, NM_001320114, NM_003744
Synonyms C14orf41; c14_5527; S171
Summary The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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