Dynamin 2 (DNM2) Human Gene Knockout Kit (CRISPR)

CAT#: KN208525BN

DNM2 - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


Rabbit Polyclonal Anti-DNM2 Antibody
    • 100 ul

CNY 1,999.00
CNY 3,280.00


DNM2 (Myc-DDK-tagged)-Human dynamin 2 (DNM2), transcript variant 1
    • 10 ug

CNY 6,376.00

Specifications

Product Data
Format 2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA mBFP-Neo
Symbol Dynamin 2
Locus ID 1785
Kit Components

KN208525G1, Dynamin 2 gRNA vector 1 in pCas-Guide CRISPR vector

KN208525G2, Dynamin 2 gRNA vector 2 in pCas-Guide CRISPR vector

KN208525BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001005360, NM_001005361, NM_001005362, NM_001190716, NM_004945
Synonyms CMT2M; CMTDI1; CMTDIB; DI-CMTB; DYN2; DYNII; LCCS5
Summary Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Documents

Other Versions

Customer Reviews 
Loading...