ThPok (ZBTB7B) Human Gene Knockout Kit (CRISPR)

CAT#: KN204105

ZBTB7B - human gene knockout kit via CRISPR, HDR mediated




 HDR-mediated knockout kit validation

  See Other Versions

CNY 12,260.00


货期*
6周

规格
    • 1 kit

Product images

经常一起买 (3)
pCAS-Scramble, pCas-Guide vector with a scrambled sequence as a negative control (10 µg)
    • 10 ug

CNY 3,710.00


ZBTB7B Antibody - C-terminal region
    • 100 ul

CNY 5,250.00


ZBTB7B (Myc-DDK-tagged)-Human zinc finger and BTB domain containing 7B (ZBTB7B)
    • 10 ug

CNY 4,016.00
CNY 5,420.00

Specifications

Product Data
Format 2 gRNA vectors, 1 GFP-puro donor, 1 scramble control
Donor DNA GFP-puro
Symbol ThPok
Locus ID 51043
Kit Components

KN204105G1, ThPok gRNA vector 1 in pCas-Guide CRISPR vector

KN204105G2, ThPok gRNA vector 2 in pCas-Guide CRISPR vector

KN204105-D, donor DNA containing left and right homologous arms and GFP-puro functional cassette.

GE100003, scramble sequence in pCas-Guide vector

Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq NM_001252406, NM_001256455, NM_015872, NR_045515, NR_046206, NR_049765
Synonyms c-KROX; CKROX; hcKROX; THPOK; ZBTB15; ZFP-67; ZFP67; ZNF857B
Summary This gene encodes a zinc finger-containing transcription factor that acts as a key regulator of lineage commitment of immature T-cell precursors. It is necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. It also functions as a transcriptional repressor of type I collagen genes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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