RBM3 Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 Luciferase-Puro donor, 1 scramble control
Donor DNA	Luciferase-Puro
Symbol	RBM3
Locus ID	5935
Kit Components	KN201659G1, RBM3 gRNA vector 1 in pCas-Guide CRISPR vector KN201659G2, RBM3 gRNA vector 2 in pCas-Guide CRISPR vector KN201659LP-D, donor DNA containing left and right homologous arms and Luciferase-Puro functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_001017430, NM_001017431, NM_006743
Synonyms	IS1-RNPL; OTTHUMP00000025800; OTTHUMP00000025802; RNA binding motif (RNP1, RRM) protein 3; RNA binding motif protein 3; RNPL; RNPL, IS1-RNPL
Summary	This gene is a member of the glycine-rich RNA-binding protein family and encodes a protein with one RNA recognition motif (RRM) domain. Expression of this gene is induced by cold shock and low oxygen tension. A pseudogene exists on chromosome 1. Multiple alternatively spliced transcript variants that are predicted to encode different isoforms have been characterized although some of these variants fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2008]

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