CD98 (SLC3A2) Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 RFP-BSD donor, 1 scramble control
Donor DNA	RFP-BSD
Symbol	CD98
Locus ID	6520
Kit Components	KN200718G1, CD98 gRNA vector 1 in pCas-Guide CRISPR vector KN200718G2, CD98 gRNA vector 2 in pCas-Guide CRISPR vector KN200718RB-D, donor DNA containing left and right homologous arms and RFP-BSD functional cassette. GE100003, scramble sequence in pCas-Guide vector
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPR technology. The system has been functionally validated for knocking-in the cassette downstream the native promoter. The efficiency of the knock-out varies due to the nature of the biology and the complexity of the experimental process.
Reference Data
RefSeq	NM_001012661, NM_001012662, NM_001012663, NM_001012664, NM_001013251, NM_002394, NR_037193
Synonyms	4F2; 4F2HC; 4T2HC; CD98; CD98HC; MDU1; NACAE
Summary	This gene is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through di-sulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized. [provided by RefSeq, Nov 2010]

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