FCGRT Human Gene Knockout Kit (CRISPR)

Specifications

Product Data
Format	2 gRNA vectors, 1 mBFP-Neo donor, 1 scramble control
Donor DNA	mBFP-Neo
Symbol	FCGRT
Locus ID	2217
Kit Components	KN200364G1, FCGRT gRNA vector 1 in pCas-Guide CRISPR vector KN200364G2, FCGRT gRNA vector 2 in pCas-Guide CRISPR vector KN200364BN-D, donor DNA containing left and right homologous arms and mBFP-Neo functional cassette. GE100003, scramble sequence in pCas-Guide vector
Reference Data
RefSeq	NM_001136019, NM_004107
Synonyms	alpha-chain; FCRN
Summary	This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

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