Mouse Nova1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nova1
Locus ID	664883
Kit Components	GA218310G1, Nova1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA218310G2, Nova1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA218310G3, Nova1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_021361, NM_001364634, NM_001364635, NM_001364636, NM_001364637, NM_001364638, NM_001364639
Synonyms	9430099M15Rik; G630039L02; Nova-1
Summary	Functions to regulate alternative splicing in neurons by binding pre-mRNA in a sequence-specific manner to activate exon inclusion. It binds specifically to the sequence UCAUY. Most likely acts to activate the inclusion of exon E3A in the glycine receptor alpha-2 chain and of exon E9 in gamma-aminobutyric-acid receptor gamma-2 subunit via a distal downstream UCAU-rich intronic splicing enhancer.[UniProtKB/Swiss-Prot Function]

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