Mouse Akirin2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Akirin2
Locus ID	433693
Kit Components	GA217573G1, Akirin2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA217573G2, Akirin2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA217573G3, Akirin2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001007589, NM_026019
Synonyms	2700059D21Rik; AA114675; AA522011; Akirin-2; AU019887
Summary	Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity). Required for embryonic development and the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6.[UniProtKB/Swiss-Prot Function]

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