Mouse Arhgap32 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Arhgap32
Locus ID	330914
Kit Components	GA216858G1, Arhgap32 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216858G2, Arhgap32 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216858G3, Arhgap32 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001195632, NM_177379
Synonyms	3426406O18Rik; Gc-gap; Grit; mKIAA0712; p200Rhogap; p250Gap; Px-rics; Rics
Summary	GTPase-activating protein (GAP) promoting GTP hydrolysis on RHOA, CDC42 and RAC1 small GTPases. May be involved in the differentiation of neuronal cells during the formation of neurite extensions. Involved in NMDA receptor activity-dependent actin reorganization in dendritic spines. May mediate cross-talks between Ras- and Rho-regulated signaling pathways in cell growth regulation. Isoform 2 has higher GAP activity.[UniProtKB/Swiss-Prot Function]

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