Mouse Gcfc2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gcfc2
Locus ID	330361
Kit Components	GA216816G1, Gcfc2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216816G2, Gcfc2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216816G3, Gcfc2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_177884
Synonyms	A130099G21; AW146020; GCF2; Tcf9
Summary	Factor that represses transcription. It binds to the GC-rich sequences (5'-GCGGGGC-3') present in the epidermal growth factor receptor, beta-actin, and calcium-dependent protease promoters. Involved in pre-mRNA splicing through regulating spliceosome C complex formation. May play a role during late-stage splicing events and turnover of excised inrons (By similarity).[UniProtKB/Swiss-Prot Function]

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