Mouse Hs3st5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hs3st5
Locus ID	319415
Kit Components	GA216275G1, Hs3st5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216275G2, Hs3st5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216275G3, Hs3st5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081208, NM_001253355, NM_001253356
Synonyms	D930005L05Rik; Gm1151; Hs3ost5
Summary	Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to position 3 of glucosamine residues in heparan. Catalyzes the rate limiting step in the biosynthesis of heparan sulfate (HSact). This modification is a crucial step in the biosynthesis of anticoagulant heparan sulfate as it completes the structure of the antithrombin pentasaccharide binding site. Also generates GlcUA-GlcNS or IdoUA-GlcNS and IdoUA2S-GlcNH2 (By similarity).[UniProtKB/Swiss-Prot Function]

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