Mouse Shc4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Shc4
Locus ID	271849
Kit Components	GA216117G1, Shc4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216117G2, Shc4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216117G3, Shc4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_199022
Synonyms	6230417E10Rik; 9930029B02Rik; Gm685; RaLP
Summary	Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.[UniProtKB/Swiss-Prot Function]

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