Mouse Mthfd1l activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Mthfd1l
Locus ID	270685
Kit Components	GA216096G1, Mthfd1l gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216096G2, Mthfd1l gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216096G3, Mthfd1l gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001170785, NM_001170786, NM_172308
Synonyms	2410004L15Rik; AI647056; Fthfsdc1
Summary	May provide the missing metabolic reaction required to link the mitochondria and the cytoplasm in the mammalian model of one-carbon folate metabolism in embryonic an transformed cells complementing thus the enzymatic activities of MTHFD2.[UniProtKB/Swiss-Prot Function]

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