Mouse Nup98 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nup98
Locus ID	269966
Kit Components	GA216062G1, Nup98 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216062G2, Nup98 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216062G3, Nup98 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001287164, NM_001287165, NM_001287166, NM_001287167, NM_022979
Synonyms	4732457F17; AI849286; Nup96
Summary	Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. NUP98 and NUP96 are involved in the bidirectional transport across the NPC. May anchor NUP153 and TPR to the NPC. In cooperation with DHX9, plays a role in transcription and alternative splicing activation of a subset of genes. Involved in the localization of DHX9 in discrete intranuclear foci (GLFG-body).[UniProtKB/Swiss-Prot Function]

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