Mouse Plch2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Plch2
Locus ID	269615
Kit Components	GA216026G1, Plch2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA216026G2, Plch2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA216026G3, Plch2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001113360, NM_175556, NM_001356470
Synonyms	A930027K05Rik; Plc-eta2; PLCeta2; Plcl4
Summary	The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. This phospholipase activity is very sensitive to calcium. May be important for formation and maintenance of the neuronal network in the postnatal brain.[UniProtKB/Swiss-Prot Function]

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