Mouse Grm4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Grm4
Locus ID	268934
Kit Components	GA215967G1, Grm4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215967G2, Grm4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215967G3, Grm4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001013385, NM_001291045, NM_001360192
Synonyms	Gprc1d; mGluR4
Summary	G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling inhibits adenylate cyclase activity (By similarity).[UniProtKB/Swiss-Prot Function]

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