Mouse Kdm4d activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Kdm4d
Locus ID	244694
Kit Components	GA215218G1, Kdm4d gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215218G2, Kdm4d gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215218G3, Kdm4d gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_173433
Synonyms	4932416A15; Jmjd2d
Summary	Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate (By similarity).[UniProtKB/Swiss-Prot Function]

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