Mouse Tox3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tox3
Locus ID	244579
Kit Components	GA215207G1, Tox3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215207G2, Tox3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215207G3, Tox3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_172913
Synonyms	500-9; BC052044; C230068E13; CAGF9; Tnrc9
Summary	Transcriptional coactivator of the p300/CBP-mediated transcription complex. Activates transactivation through cAMP response element (CRE) sites. Protects against cell death by inducing antiapoptotic and repressing pro-apoptotic transcripts. Stimulates transcription from the estrogen-responsive or BCL-2 promoters. Required for depolarization-induced transcription activation of the C-FOS promoter in neurons. Associates with chromatin to the estrogen-responsive C3 promoter region (By similarity).[UniProtKB/Swiss-Prot Function]

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