Mouse Chd2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Chd2
Locus ID	244059
Kit Components	GA215174G1, Chd2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215174G2, Chd2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215174G3, Chd2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001081345
Synonyms	2810013C04Rik; 2810040A01Rik; 5630401D06Rik; AI851092; BC029703; CHD-2
Summary	DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3. Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the onset of myogenic gene expression, promoting their expression.[UniProtKB/Swiss-Prot Function]

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