Mouse Chd2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Chd2
Locus ID	244059
Kit Components	GA215174G1, Chd2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215174G2, Chd2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215174G3, Chd2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081345
Synonyms	2810013C04Rik; 2810040A01Rik; 5630401D06Rik; AI851092; BC029703; CHD-2
Summary	DNA-binding helicase that specifically binds to the promoter of target genes, leading to chromatin remodeling, possibly by promoting deposition of histone H3.3. Involved in myogenesis via interaction with MYOD1: binds to myogenic gene regulatory sequences and mediates incorporation of histone H3.3 prior to the onset of myogenic gene expression, promoting their expression.[UniProtKB/Swiss-Prot Function]

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