Mouse Elfn1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Elfn1
Locus ID	243312
Kit Components	GA215109G1, Elfn1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215109G2, Elfn1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215109G3, Elfn1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_175522
Synonyms	A930017N06Rik; AI197272; Ppp1r28
Summary	Postsynaptic protein that regulates circuit dynamics in the central nervous system by modulating the temporal dynamics of interneuron recruitment. Specifically present in excitatory synapses onto oriens-lacunosum molecular (OLM) interneurons and acts as a regulator of presynaptic release probability to direct the formation of highly facilitating pyramidal-OLM synapses. Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes.[UniProtKB/Swiss-Prot Function]

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