Mouse Pde5a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pde5a
Locus ID	242202
Kit Components	GA215032G1, Pde5a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA215032G2, Pde5a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA215032G3, Pde5a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_153422
Synonyms	Cgbpde; Cn5n; Pde5; Pde5a1; PDE5a2
Summary	Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP. Specifically regulates nitric-oxide-generated cGMP.[UniProtKB/Swiss-Prot Function]

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