Mouse Pde11a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pde11a
Locus ID	241489
Kit Components	GA214995G1, Pde11a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214995G2, Pde11a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214995G3, Pde11a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001081033
Synonyms	6330414F14Rik; A630086N24Rik; Gm350; PDE11A1
Summary	Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively (By similarity).[UniProtKB/Swiss-Prot Function]

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