Mouse Irf2bpl activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Irf2bpl
Locus ID	238330
Kit Components	GA214790G1, Irf2bpl gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214790G2, Irf2bpl gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214790G3, Irf2bpl gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_145836
Synonyms	6430527G18Rik; Eap1
Summary	Probable E3 ubiquitin protein ligase involved in the proteasome-mediated ubiquitin-dependent degradation of target proteins. Through the degradation of CTNNB1, functions downstream of FOXF2 to negatively regulate the Wnt signaling pathway. Probably plays a role in the development of the central nervous system and in neuronal maintenance (By similarity). Also acts as a transcriptional regulator of genes controlling female reproductive function. May play a role in gene transcription by transactivating GNRH1 promoter and repressing PENK promoter (By similarity).[UniProtKB/Swiss-Prot Function]

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