Mouse Csgalnact1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Csgalnact1
Locus ID	234356
Kit Components	GA214523G1, Csgalnact1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA214523G2, Csgalnact1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA214523G3, Csgalnact1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001252623, NM_172753, NM_001364256
Synonyms	4732435N03Rik; CSGalNAcT-1
Summary	Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage formation, and subsequent endochondral ossification (PubMed:17145758, PubMed:21148564). Moreover, is involved in the metabolism of aggrecan (PubMed:21148564).[UniProtKB/Swiss-Prot Function]

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