Mouse Man1b1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Man1b1
Locus ID	227619
Kit Components	GA213941G1, Man1b1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213941G2, Man1b1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213941G3, Man1b1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001029983
Synonyms	E430019H13Rik; ERMan1; Gm108; MANA-ER
Summary	Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man(9)GlcNAc(2) to produce Man(8)GlcNAc(2), but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man(5-6)GlcNAc(2) (By similarity).[UniProtKB/Swiss-Prot Function]

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