Mouse Farp2 activation kit by CRISPRa
CAT#: GA213925
Farp2 CRISPRa kit - CRISPR gene activation of mouse FERM, RhoGEF and pleckstrin domain protein 2
CN¥ 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Farp2 |
Locus ID | 227377 |
Kit Components | GA213925G1, Farp2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213925G2, Farp2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213925G3, Farp2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_145519 |
Synonyms | AI465173; BC009153; D030026M03Rik; Fir; mKIAA0793 |
Summary | Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity (PubMed:23375260 and PubMed:20702777). Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN505757 | Farp2 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CN¥ 8,680.00 |