Mouse Ndufs1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ndufs1
Locus ID	227197
Kit Components	GA213912G1, Ndufs1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA213912G2, Ndufs1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA213912G3, Ndufs1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001160038, NM_001160039, NM_001160040, NM_145518
Synonyms	5830412M15Rik; 9930026A05Rik
Summary	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). This is the largest subunit of complex I and it is a component of the iron-sulfur (IP) fragment of the enzyme. It may form part of the active site crevice where NADH is oxidized (By similarity).[UniProtKB/Swiss-Prot Function]

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